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The process of developing new blood vessels. Angiogenesis is important in the normal development of the embryo and fetus. It also appears important to tumor formation. Certain proteins, including angiostatin and endostatin, secreted by tumors work (at least in mice) by interfering with the blood supply tumors need. Angiostatin is a piece of a larger and very common protein, plasminogen, that the body uses in blood clotting. Endostatin is a piece of a different protein, collagen 18, that is in all blood vessels.

Tumor angiogenesis is the growth of blood vessels from surrounding tissue to a solid tumor. This is caused by the release of chemicals by the tumor.

See also:

* Angiogenesis

* Angiogenesis and Cancer

* Angiogenesis and Cancer Control

* Angiogenesis Inhibitors and Cancer

* Angiogenic role of LYVE-1-positive macrophages in adipose tissue

* Angiopoietins and angiopoietin-like proteins in angiogenesis

* PIGF antagonizes VEGF induced angiogenesis - tumor growth

* Expression of VEGF-C angiogenesis, lymphangiogenesis Cancer

*Genetics Glossary

glossary/angiogenesis.txt · Last modified: 2012/10/16 14:40 (external edit)